EasterBlack-owned or founded brands at TargetGroceryClothing, Shoes & AccessoriesBabyHomeFurnitureKitchen & DiningOutdoor Living & GardenToysElectronicsVideo GamesMovies, Music & BooksSports & OutdoorsBeautyPersonal CareHealthPetsHousehold EssentialsArts, Crafts & SewingSchool & Office SuppliesParty SuppliesLuggageGift IdeasGift CardsClearanceTarget New ArrivalsTarget Finds#TargetStyleTop DealsTarget Circle DealsWeekly AdShop Order PickupShop Same Day DeliveryRegistryRedCardTarget CircleFind Stores

Sponsored

Acetaminophen & Aspirin (NSAID) Added-Strength Pain Reliever Caplets - up&up™

Acetaminophen & Aspirin (NSAID) Added-Strength Pain Reliever Caplets - up&up™ - 2 of 4Acetaminophen & Aspirin (NSAID) Added-Strength Pain Reliever Caplets - up&up™ - 3 of 4Acetaminophen & Aspirin (NSAID) Added-Strength Pain Reliever Caplets - up&up™ - 4 of 4
Acetaminophen & Aspirin (NSAID) Added-Strength Pain Reliever Caplets - up&up™ - 1 of 4
$6.79 when purchased online
Target Online store #3991

About this item

Highlights

  • Packaging may vary. Same trusted quality
  • Pain reliever caplets contain acetaminophen, aspirin and caffeine
  • Helps to relieve headache and migraine pain, as well as muscle aches and other pain
  • Compare to the active ingredients in Excedrin Extra Strength

Description

Go through your day with relief from headaches and other pains with the help of the Acetaminophen and Aspirin Added-Strength Pain Reliever Caplets from up&up™. With a combination of acetaminophen, aspirin and caffeine, you'll find quick relief from throbbing headaches or migraines. With each pain relief caplet, you can relieve the pain caused by muscle aches and menstrual cramps as well headache pain. The added caffeine helps to relax muscle contractions and improve mental altertness as you head off to work or spend time with loved ones.


We believe making smart choices for the people, places, and pets in your life should be easy and affordable. And, having quality you can trust should be a given. That’s why you can count on our promise – caring for your everyday in every way.

Satisfaction guaranteed – Love it or your money back.
Suggested Age: 12 Years and Up
Health Facts: Contains Acetaminophen, Contains Caffeine, Contains Aspirin
Product Warning: Consult a doctor if you have heart disease, Contains Acetaminophen, do not use if you have a bleeding problem, not for children under the age of 12, consult a doctor if you have high blood pressure, do not use if you have kidney disease, Contains Caffeine, do not use if you are pregnant
Active Ingredient Strength Value: 250 Milligrams
Product Form: Caplet
Primary Active Ingredient: Acetaminophen
Package Quantity: 275
TCIN: 11004687
UPC: 349483370720
Item Number (DPCI): 094-01-0124
Origin: Made in the USA or Imported
Healthcare Disclaimer:
Content on this site is for reference purposes only. Target does not represent or warrant that the nutrition, ingredient, allergen and other product information on our Web or Mobile sites are accurate or complete, since this information comes from the product manufacturers. On occasion, manufacturers may improve or change their product formulas and update their labels. We recommend that you do not rely solely on the information presented on our Web or Mobile sites and that you review the product's label or contact the manufacturer directly if you have specific product concerns or questions. If you have specific healthcare concerns or questions about the products displayed, please contact your licensed healthcare professional for advice or answers.
If the item details above aren’t accurate or complete, we want to know about it.

Active ingredients

acetaminophen 250.0mg aspirin (nsaid*) *nonsteroidal anti-inflammatory drug 250.0mg caffeine 65.0mg

Purpose

Pain reliever Pain reliever Pain reliever aid

Uses

Uses Temporarily relieves minor aches and pains due to: headache a cold arthritis muscular aches toothache premenstrual and menstrual cramps

Directions

Directions do not use more than directed drink a full glass of water with each dose adults and children 12 years of age and over: take 2 caplets every 6 hours; not more than 8 caplets in 24 hours children under 12 years: ask a doctor

Other information

Other information store at 20°-25°C (68°-77°F); excursions permitted between 15°-30°C (59°-86°F) use by expiration date on package

Inactive ingredients

carnauba wax, colloidal silicon dioxide, hypromellose, microcrystalline cellulose, mineral oil, povidone, pregelatinized starch, sodium starch glycolate, stearic acid, titanium dioxide

Shipping details

Estimated ship dimensions: 5.4331 inches length x 3.7795 inches width x 2.6772 inches height
Estimated ship weight: 0.5291 pounds

Return details

This item can be returned to any Target store or Target.com.
This item must be returned within 365 days of the date it was purchased in store, shipped, delivered by a Shipt shopper, or made ready for pickup.
See the return policy for complete information.

Related Categories

Summary of reviews

This product is highly regarded for its effectiveness in relieving migraines and headaches, often compared favorably to name-brand alternatives. Guests appreciate its fast-acting formula and affordability, making it a staple in their medicine cabinets. Many find it works just as well as more expensive options, providing significant relief at a fraction of the cost. However, some guests have reported issues with taste and stomach discomfort, which may affect their overall experience.
    Summary created by AI from text of reviews reflecting recent feedback provided across different star ratings (includes incentivized reviews)
    4.7 out of 5 stars with 1362 reviews
    quality: 4.35 out of 5
    value: 4.57 out of 5
    84% would recommend
    139 recommendations

    Works great!

    5 out of 5 stars
    Thumbs up graphic, would recommend
    Rah - 8 days ago, Verified purchaser
    This stuff is nothing sort of amazing. Not only is it affordable, it works fast on killer headaches and relieves other body aches.
    quality: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?

    Dont recommend

    1 out of 5 stars
    Thumbs down graphic, would not recommend
    Cait - 20 days ago
    Caused stomach pains and made me throw up after taking
    quality: 1 out of 5
    value: 1 out of 5
    Did you find this review helpful?

    Works great!

    5 out of 5 stars
    Thumbs up graphic, would recommend
    TargetFun - 1 month ago, Verified purchaser
    I always buy the Up and Up brand for medications. Work just like the name brand for a fraction of the price!
    quality: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?

    Not a good generic for me

    2 out of 5 stars
    Northwoods 25 - 1 month ago, Verified purchaser
    This generic brand didn’t work for me. It took several hours before I had slight relief. I’ve taken generic Excedrin brands before but this one doesn’t work for me…too bad. Seems some others have had similar results.
    Did you find this review helpful?

    Headache be gone !!!!

    5 out of 5 stars
    Thumbs up graphic, would recommend
    Dsusieq369 - 2 months ago, Verified purchaser
    These are just like Excedrin and makes the headach go away
    quality: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?

    Useless

    1 out of 5 stars
    Thumbs down graphic, would not recommend
    michaela - 3 months ago
    If you suffer from *true* migraines then don’t waste any time or money on these and stick to excederin.
    quality: 1 out of 5
    value: 1 out of 5
    1 guest found this review helpful. Did you?

    love!!

    5 out of 5 stars
    Thumbs up graphic, would recommend
    gmatthes - 4 months ago, Verified purchaser
    love and way cheaper than the alternative
    quality: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?

    Necessity!

    5 out of 5 stars
    Thumbs up graphic, would recommend
    shopaholic - 4 months ago, Verified purchaser
    These are the only thing that work for my headaches. Glad they make a generic, target offers a good price compared to name brand.
    Did you find this review helpful?

    "Excedrin-Level Relief Without the Excedrin Price - Try Up & Up!

    5 out of 5 stars
    Thumbs up graphic, would recommend
    IceBlue37 - 4 months ago, Verified purchaser
    Comparable to Excedrin Extra Strength at a much better price. I've been pleasantly surprised by how well these Up & Up pain relievers work. They're my go-to for headache relief and haven't failed me yet. They provide the same relief as the more expensive Excedrin, so I'll definitely be sticking with these from now on.
    1 guest found this review helpful. Did you?

    Works just as well as name brand

    5 out of 5 stars
    Thumbs up graphic, would recommend
    LisaL - 5 months ago, Verified purchaser
    Works fine! Don’t waste your money on name brand meds.
    quality: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?

    Helps sometimes

    5 out of 5 stars
    Thumbs up graphic, would recommend
    qsmama - 5 months ago, Verified purchaser
    I’ve suffered from migraines since I was 17 and unfortunately my son gets them as well. This is one of only two medicines that helps both of us. If we take it as soon as the migraine starts, it definitely helps. I will say that for a more severe one, we both have to use something else but overall I think it’s worth a try for migraine sufferers. Also, it’s a great price!
    quality: 5 out of 5
    value: 5 out of 5
    1 guest found this review helpful. Did you?

    Dont recommend

    1 out of 5 stars
    Thumbs down graphic, would not recommend
    Polly - 5 months ago, Verified purchaser
    Does not work as well as excedrin and headache did not go away
    quality: 1 out of 5
    value: 1 out of 5
    Did you find this review helpful?

    Headache gone!

    5 out of 5 stars
    Thumbs up graphic, would recommend
    den - 6 months ago, Verified purchaser
    This works just as well as name brand products. Save yourself some money and use this! No brainer!
    value: 5 out of 5
    quality: 5 out of 5
    1 guest found this review helpful. Did you?

    Name brand quality

    5 out of 5 stars
    Thumbs up graphic, would recommend
    Lp - 6 months ago, Verified purchaser
    Gets the job done just as good as the name brand and a fraction of the price!
    quality: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?

    Really affordable

    5 out of 5 stars
    Thumbs up graphic, would recommend
    IceCream - 6 months ago
    Works just like Tylenol and way more affordable.
    value: 5 out of 5
    quality: 5 out of 5
    Did you find this review helpful?

    These work!

    5 out of 5 stars
    Thumbs up graphic, would recommend
    - 6 months ago, Verified purchaser
    I suffer from serious migraines. I even got both my daith pierced, which only helped for a short period of time. Aleve use to work too, but it sadly no longer works. I refuse to take prescribed scripts since they always have a side effect, so I thought I would give this a chance, and it worked! Not saying it works immediately, but it works on most of my bad migraine days!!
    quality: 5 out of 5
    value: 5 out of 5
    Did you find this review helpful?

    Pre migraine lifesaver

    5 out of 5 stars
    Thumbs up graphic, would recommend
    ADoyle - 6 months ago, Verified purchaser
    Prone to migraines, when I feel the beginnings I pop one of these and usually does the trick. Lifesaver
    Did you find this review helpful?

    Medicine bag must have.

    5 out of 5 stars
    Thumbs up graphic, would recommend
    MoniLuvs24_7 - 6 months ago, Verified purchaser
    Occasionally I get hit with a migraine but I keep a bottle of this on hand to help me tackle those migraines.
    value: 5 out of 5
    quality: 5 out of 5
    Did you find this review helpful?

    Headache relief

    5 out of 5 stars
    Thumbs up graphic, would recommend
    Cynthia - 7 months ago
    Works great. It just as good as the name brand.
    Did you find this review helpful?

    Works

    5 out of 5 stars
    Thumbs up graphic, would recommend
    HR - 7 months ago
    Works just as well as the name brand for a fraction of the price.
    quality: 5 out of 5
    value: 5 out of 5
    1 guest found this review helpful. Did you?

    Get top deals, latest trends, and more.

    Privacy policy

    Footer

    About Us

    About TargetCareersNews & BlogTarget BrandsBullseye ShopSustainability & GovernancePress CenterAdvertise with UsInvestorsAffiliates & PartnersSuppliersTargetPlus

    Help

    Target HelpReturnsTrack OrdersRecallsContact UsFeedbackAccessibilitySecurity & FraudTeam Member Services

    Stores

    Find a StoreClinicPharmacyOpticalMore In-Store Services

    Services

    Target Circle™Target Circle™ CardTarget Circle 360™Target AppRegistrySame Day DeliveryOrder PickupDrive UpFree 2-Day ShippingShipping & DeliveryMore Services
    PinterestFacebookInstagramXYoutubeTiktokTermsCA Supply ChainPrivacyCA Privacy RightsYour Privacy ChoicesInterest Based AdsHealth Privacy Policy