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About this item
Highlights
- Die Bioseparationstechnik ist eine multidisziplinäre Anwendung technischer und biologischer Prinzipien zum Design von Adsorptionsmitteln, Systemen und Prozessen für die Trennung von Biomolekülen.
- About the Author: MICHAEL R. LADISCH, PhD, is Distinguished Professor in the Department of Agricultural and Biological Engineering and the Department of Biomedical Engineering, and the Director of the Laboratory of Renewable Resources Engineering, at Purdue University in West Lafayette, Indiana.
- 760 Pages
- Technology, Chemical & Biochemical
Description
Book Synopsis
Die Bioseparationstechnik ist eine multidisziplinäre Anwendung technischer und biologischer Prinzipien zum Design von Adsorptionsmitteln, Systemen und Prozessen für die Trennung von Biomolekülen. Dieses praxisorientierte Buch will vor allem Biochemiker und Chemiker anhand zahlreicher Beispiele und Fallstudien in die industrielle Umsetzung der Verfahren einführen. Neben den naturwissenschaftlichen und technischen Grundlagen werden auch ökonomische Aspekte wie die Abschätzung von Kosten einzelner Prozeduren ausführlich besprochen.From the Back Cover
Multidisciplinary resource for graduate studies and the biotechnology industry Knowledge of the genetic basis of biological functioning continues to grow at an astronomical rate, as do the challenges and opportunities of applying this information to the production of therapeutic compounds, specialty biochemicals, functional food ingredients, environmentally friendly biocatalysts, and new bioproducts from renewable resources. While genetic engineering of living organisms transforms the science of genomics into treatments for cancer, diabetes, and heart disease, or products for industry and agriculture, the science and technology of bioseparations are the keys to delivering these products in a purified form suitable for use by people. The methods, theory, and materials that reduce the science of bioseparations to practice, whether in the laboratory or the plant, are the subjects of Bioseparations Engineering. Examples address purification of biomolecules ranging from recombinant proteins to gene therapy products, with footnotes detailing economics of the products. Mechanistic analysis and engineering design methods are given for:* Isocratic and gradient chromatography
* Sedimentation, centrifugation, and filtration
* Membrane systems
* Precipitation and crystallization Topics addressed within this framework are: stationary phase selection; separations development; modeling of ion exchange, size exclusion, reversed phase, hydrophobic interaction, and affinity chromatography; the impact of regulatory issues on chromatography process design; organization of separation strategies into logical sequences of purification steps; and bridges between molecular biology, combinatorial methods, and separations science. A result of teaching and developing the subject matter over ten years, Bioseparations Engineering is an ideal text for graduate students, as well as a timely desk book for process engineers, process scientists, researchers, and research associates in the pharmaceutical, food, and life sciences industries.
Review Quotes
"a comprehensive text that has brought together the theory and practice of bioseperations in an intelligent and well-presented fashion." (Bioseperations Engineering (Food & Bioproducts Processing, December 2001)
"...Ladish reviews the techniques that have been developed over the past couple decades...in the hope that the explanations will apply to bioproducts not yet invented and biological molecules not yet produced...as well as to those currently being used." (SciTech Book News, Vol. 25, No. 4, December 2001)
About the Author
MICHAEL R. LADISCH, PhD, is Distinguished Professor in the Department of Agricultural and Biological Engineering and the Department of Biomedical Engineering, and the Director of the Laboratory of Renewable Resources Engineering, at Purdue University in West Lafayette, Indiana.Dimensions (Overall): 9.54 Inches (H) x 6.4 Inches (W) x 1.54 Inches (D)
Weight: 2.54 Pounds
Suggested Age: 22 Years and Up
Sub-Genre: Chemical & Biochemical
Genre: Technology
Number of Pages: 760
Publisher: Wiley-Interscience
Format: Hardcover
Author: Michael R Ladisch
Language: English
Street Date: March 27, 2001
TCIN: 93891522
UPC: 9780471244769
Item Number (DPCI): 247-10-5761
Origin: Made in the USA or Imported
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Estimated ship dimensions: 1.54 inches length x 6.4 inches width x 9.54 inches height
Estimated ship weight: 2.54 pounds
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