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High-Throughput Mass Spectrometry in Drug Discovery - by Chang Liu & Hui Zhang (Hardcover)
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Highlights
- High-Throughput Mass Spectrometry in Drug Discovery Apply mass spectrometry to every phase of new drug discovery with this cutting-edge guide Mass spectrometry is a technique that identifies and characterizes compounds based on their mass -- the fundamental molecular characteristic.
- About the Author: Chang Liu, Ph.D., is a Staff Research Scientist at SCIEX, a global leader in the design and production of mass spectrometers.
- 512 Pages
- Science, Chemistry
Description
About the Book
"This book covers fundamentals, experimental details, and applications of state-of-art technologies that enable high-throughput MS-based screens in supporting drug discovery. These include hit discovery by label-free screening, synthetic reaction optimization, lead optimization and SAR support, chromatography, and ADME (absorption, distribution, metabolism, and excretion) screening"--Book Synopsis
High-Throughput Mass Spectrometry in Drug DiscoveryApply mass spectrometry to every phase of new drug discovery with this cutting-edge guide
Mass spectrometry is a technique that identifies and characterizes compounds based on their mass -- the fundamental molecular characteristic. It has become an invaluable analytical tool in various disciplines, industries, and research fields. It has become particularly central to new drug discovery and development, which broadly deploys mass spectrometry at every phase. The pharmaceutical industry has become one of the main drivers of technological development in mass spectrometry.
High-Throughput Mass Spectrometry in Drug Discovery offers a comprehensive introduction to mass spectrometry and its applications in pharmaceutical discovery. It covers the foundational principles and science of mass spectrometry before moving to specific experimental methods and their applications at various stages of drug discovery. Its thorough treatment and detailed guidance make it an invaluable tool for pharmaceutical research and development.
High-Throughput Mass Spectrometry in Drug Discovery readers will also find:
- Detailed analysis of techniques, including label-free screening, synthetic reaction optimization, and more
- An authorial team with extensive combined experience in research and industrial applications
- Technical strategies with the potential to accelerate quantitative bioanalysis in drug discovery
High-Throughput Mass Spectrometry in Drug Discovery is essential for analytical, bioanalytical, and medicinal chemists working in the pharmaceutical industry and for any researchers and graduate students interested in drug discovery and development.
From the Back Cover
Apply mass spectrometry to every phase of new drug discovery with this cutting-edge guide
Mass spectrometry is a technique that identifies and characterizes compounds based on their mass -- the fundamental molecular characteristic. It has become an invaluable analytical tool in various disciplines, industries, and research fields. It has become particularly central to new drug discovery and development, which broadly deploys mass spectrometry at every phase. The pharmaceutical industry has become one of the main drivers of technological development in mass spectrometry.
High-Throughput Mass Spectrometry in Drug Discovery offers a comprehensive introduction to mass spectrometry and its applications in pharmaceutical discovery. It covers the foundational principles and science of mass spectrometry before moving to specific experimental methods and their applications at various stages of drug discovery. Its thorough treatment and detailed guidance make it an invaluable tool for pharmaceutical research and development.
High-Throughput Mass Spectrometry in Drug Discovery readers will also find:
- Detailed analysis of techniques, including label-free screening, synthetic reaction optimization, and more
- An authorial team with extensive combined experience in research and industrial applications
- Technical strategies with the potential to accelerate quantitative bioanalysis in drug discovery
High-Throughput Mass Spectrometry in Drug Discovery is essential for analytical, bioanalytical, and medicinal chemists working in the pharmaceutical industry and for any researchers and graduate students interested in drug discovery and development.
About the Author
Chang Liu, Ph.D., is a Staff Research Scientist at SCIEX, a global leader in the design and production of mass spectrometers. He has published extensively on using mass spectrometry in drug discovery and development.
Hui Zhang, Ph.D., is the Vice President of Analytical Technologies at Entos, a biotech company focusing on Artificial Intelligence and High-Throughput Experimentation driving drug discovery. He has published widely on mass spectrometry and its pharmaceutical applications through his previous tenure at Pfizer.